Controlled Cell Adhesion on Poly(dopamine) Interfaces Photo-Patterned with Non-Fouling Brushes

  • chair:

    Rodriguez-Emmenegger, C. / Preuss, C. / Yameen, B. / Pop-Georgievski, O. / Bachmann, M. / Mueller, J. / Bruns, M. / Goldmann, A. / Bastmeyer, M. / Barner-Kowollik, C. (2013)
  • place:

    Advanced Materials 25 (2013), 42, 6123-6127
  • Date: 2013

  • Rodriguez-Emmenegger, C. / Preuss, C. / Yameen, B. / Pop-Georgievski, O. / Bachmann, M. / Mueller, J. / Bruns, M. / Goldmann, A. / Bastmeyer, M. / Barner-Kowollik, C. (2013): „Controlled Cell Adhesion on Poly(dopamine) Interfaces Photo-Patterned with Non-Fouling Brushes“. In: Advanced Materials 25 (2013), 42, 6123-6127

Abstract

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Bioinspired poly(dopamine) (PDA) films are merged with antifouling poly(MeOEGMA) brushes utilizing a nitrile imine-mediated tetrazole-ene cycloaddition (NITEC)-based phototriggered surface encoding protocol.

The antifouling brushes were photopatterned on PDA surfaces, leading cells to form confluent layers in the non-irradiated sections, while no adhesion occurred on the brushes resulting in a remarkably precise cell pattern. The presented strategy paves the way for the design of tailor-made patterned cell interfaces.