| Titel | chair | place |
|---|---|---|
| *ARTIKEL* | Self-Driving Lab for Solid-Phase Extraction Process Optimization and Application to Nucleic Acid Purification |
Putz, S. / Döttling, J. / Ballweg, T. / Tschöpe, A. / Biniyaminov, V. / Franzreb, M. (2024) |
| The role of TiO2 and gC3N4 bimetallic catalysts in boosting antibiotic resistance gene removal through photocatalyst assisted peroxone process | Cong, X. / Maziersk, P. / Miodyńska, M. / Zaleska-Medynska, A. / Horn, H. / Schwartz, T. / Gmurek, M. (2024) |
scientific reports, 2024, 14, 22897 |
| Physicochemical and Electrochemical Investigation of Naturally Occurring Quinones for Application toward Electrochemically Mediated Carbon Dioxide Capture | Tan, K.-J. / Kuger, L. / Franzreb, M. / Hatton, T.A. (2024) |
J. Phys. Chem. C, 2024, 128, 39, 16467–16480 |
| All-atom modeling of methacrylate-based multi-modal chromatography resins for Langmuir constant prediction of peptides | Ballweg, T. / Liu, M. / Grimm, J. / Sedghamiz, E. / Wenzel, W. / Franzreb, M. (2024) |
Journal of Chromatography A, 2024, 1730, 465089 |
| Efficient derivatization-free monitoring of glycosyltransferase reactions via flow injection analysis-mass spectrometry for rapid sugar analytics | Thiele, U. / Crocoll, C. / Tschöpe, A. / Drayß, C. / Kirschhöfer, F. / Nusser, M. / Brenner-Weiß, G. / Franzreb, M. / Bleher, K. (2024) |
Anal Bioanal Chem, 2024, 416, 23, 5191-5203, 10.1007/s00216-024-05457-9. |
| Deep Learning-Based Classification of Histone–DNA Interactions Using Drying Droplet Patterns | Vaez, S. / Dadfar, B. / Koenig, M. / Franzreb, M. / Lahann, J. (2024) |
small Science Wiley-VCH, 2024, doi.org/10.1002/smsc.202400252 |
| Illuminating a biologics development challenge: systematic characterization of CHO cell-derived hydrolases identified in monoclonal antibody formulations | Maier, M. / Weiß, L. / Zeh, N. / Schmieder-Todtenhaupt, V. / Dehghani, A. / Felix, M. / Heinzelmann, D. / Lindner, B. / Schmidt, M. / Studts, J. / Schulz, P. / Reisinger, B. / Otte, K. / Franzreb, M. / Lakatos, D. / Fischer, S. (2024) |
MABS, 2024, 16, 1, 2375798, doi.org/10.1080/19420862.2024.2375798 |
| Tailoring polishing steps for effective removal of polysorbate-degrading host cell proteins in antibody purification | Maier, M. / Schneider, S. / Weiss, L. / Fischer, S. / Lakatos, D. / Studts, J. / Franzreb, M. (2024) |
Biotechnology and Bioengineering, 2024, 1–15., doi.org/10.1002/bit.28767 |
| A Simple and Sensitive Approach for Real‐Time Sensing of Enzymatically Catalyzed Hydrogelation | Putz, S. / Kassar, M: / Oelschlaeger, C. / Franzreb, M. / Kabay, G. (2024) |
Adv. Funct. Mater., 2024, 2316469, doi.org/10.1002/adfm.202316469 |
| Bacterial decontamination of process liquids and paints in E-coating lines by pulsed electric field treatment | Gusbeth, C. / Krolla, P. / Bruchmann, J. / Schwartz, T. / Müller, G. / Frey, W. (2024) |
J Coat Technol Res, 2024, doi.org/10.1007/s11998-023-00901-4 |
| Investigating Dynamic Changes in 3D-Printed Covalent Adaptable Polymer Networks | Jia, Y. / Tsotsalas, M. / Spiegel, C. / Zimmermann, D. / Blasco, E. / Wilhelm, M. / Huber, B. / Mutlu, H. / Theato, P. / Diehm, J. / Franzreb, M. (2024) |
Forschungsdaten KIT |
| Magnetic Particle Fractionation and In-line Characterization for Enhancing Magnetic Particle Imaging Tracers | Kuger, L. / Lux, E. / Franke, J. / Stoer, P. / Löwa, N. / Franzreb, M. (2024) |
International Journal on Magnetic Particle Imaging IJMPI, 2024,10,1, 1 |
| Development of standardization strategies for reproducible extrusion-based 3D bioprinting processes | Strauß, S. / Hubbuch, J. / Klahn, C. (2024) |
Hochschulschrift KIT |
| Regression Metamodel-Based Digital Twin for an Industrial Dynamic Crossflow Filtration Process | Heusel, M. / Grim, G. / Rauhut, J. / Franzreb, M. (2024) |
Bioengineering 2024, 11, 212, doi.org/10.3390/bioengineering11030212 |
| Nano‐ and Microscale Confinements in DNA‐Scaffolded Enzyme Cascade Reactions | Kröll, S. / Burgahn, T. / Rabe, K.S. / Franzreb, M. / Niemeyer, C.M. (2024) |
NanoMicoSmall, 2024, 20, 7 |
| Micro simulated moving bed chromatography-mass spectrometry as a continuous on-line process analytical tool | Diehm, J. / Witting, L. / Kirschhöfer, F. / Brenner-Weiß, G. / Franzreb, M. (2024) |
Analytical and Bioanalytical Chemistry, 2024, 416, 373–386 |
| Application of Raman spectroscopy during pharmaceutical process development for determination of critical quality attributes in Protein A chromatography | Chen, J. / Wang, J. / Hess, R. / Wang, G. / Studts, J. / Franzreb, M. (2024) |
Journal of Chromatography A, 2024, 1718, 464721 |
| Design of a Magnetic Field-Controlled Chromatography Process for Efficient and Selective Fractionation of Rare Earth Phosphors from End-of-Life Fluorescent Lamps | Kuger, L. / Franzreb, M. (2024) |
ACS Sustainable Chem. Eng. 2024, doi.org/10.1021/acssuschemeng.3c05707 |
| Synergies of pH-induced calcium phosphate precipitation and magnetic separation for energy-efficient harvesting of freshwater microalgae | Kendir, S. / Franzreb, M. (2024) |
Bioresource Technology, 2024, 391, Part B, 129964 |
| Effect of glyphosate, its metabolite AMPA, and the glyphosate formulation Roundup® on brown trout (Salmo trutta f. fario) gut microbiome diversity | Hembach, N. / Drechsel, V. / Sobol, M. / Kaster, A.-K. / Köhler, H.-R. / Triebskorn, R. / Schwartz, T. (2024) |
Frontiers in Microbiology, 2024, DOI 10.3389/fmicb.2023.1271983 |
| Thermo-cyclically operated metal oxide gas sensor arrays for analysis of dissolved volatile organic compounds in fermentation processes: Part II – Quasi online monitoring in biogas fermentation | Ojha, B. / Wilke, A. / Brämer, R. / Franzreb, M. / Kohler, H. (2024) |
Sensing and Bio-Sensing Research, 2024, 43, 100606 |
| On the reproducibility of extrusion-based bioprinting: round robin study on standardization in the field | Grijalva Garces, D. / Strauß, S. / Gretzinger, S. / Schmieg, B. / Jüngst, T. / Groll, J. / Meinel, L. / Schmidt, I. / Hartmann, H. / Schenke-Layland, K. / Brandt, N. / Selzer, M. / Zimmermann, S. / Koltay, P. / Southan, A. / Tovar, G. E. M. / Schmidt, S. / Weber, A. / Ahlfeld, T. / Gelinsky, M. / Scheibel, T. / Detsch, R. / Boccaccini, A.R. / Naolou, T. / Lee-Thedieck, C. / Willems, C. / Groth, T. / Allgeier, S. / Köhler, B. / Friedrich, T. / Briesen, H. / Buchholz, J. / Paulus, D. / von Gladiss, A. / Hubbuch, J. (2024) |
Biofabrication 2024,16, 1, DOI 10.1088/1758-5090/acfe3b |
| Titel | place | short description | |
|---|---|---|---|
| Deep Learning-Based Classification of Histone–DNA Interactions Using Drying Droplet Patterns | small Science Wiley-VCH, 2024, doi.org/10.1002/smsc.202400252 |
Abstract Developing scalable and accurate predictive analytical methods for the classification of protein-DNA binding is critical for advancing our understanding of molecular biology, disease mechanisms, and a wide spectrum of biotechnological and medical applications. It is discovered that histone–DNA interactions can be stratified based on stain patterns created by the deposition of various nucleoprotein solutions onto a substrate. In this study, a deep-learning neural network is applied to categorize polarized light microscopy images of drying droplet deposits originating from different histone–DNA mixtures. These DNA stain patterns featured high reproducibility across different species and thus enabled comprehensive DNA categorization (100% accuracy) and accurate prediction of their respective binding affinities to histones. Eukaryotic DNA, which has a higher binding affinity to mammalian histones than prokaryotic DNA, is associated with a higher overall prediction accuracy. For a given species, the average prediction accuracy increased with DNA size. To demonstrate generalizability, a pre-trained CNN is challenged with unknown images that originated from DNA samples of species not included in the training set. The CNN classified these unknown histone-DNA samples as either strong or medium binders with 84.4% and 96.25% accuracy, respectively.
|
Publications 2024 / Chemisty of oxydic and organic Interfaces (COOI) + Robot-assisted and Information-based Material Synthesis (RIMS)
| Titel | chair | place |
|---|---|---|
| Enhanced Performance of Laser-Induced Graphene Supercapacitors via Integration with Candle-Soot Nanoparticles | Ghosh, A. / Kaur, S. / Verma, G. / Dolle, C. / Azmi, R. / Heissler, S. / Eggeler, Y.M. / Mondal, K. / Mager, D. / Gupta, A. / Korvink, J.G. / Wang, D.Y. / Sharma, A. / Islam, M. (2024) |
CS Appl. Mater. Interfaces 2024, doi.org/10.1021/acsami.4c07094
|
| Metal-Organic Framework Hybrid Materials: Developing Tailored Synthesis Approaches for Biology and Medicine | Wagner, I. / Tsotsalas, M. / Théato, P. (2024) |
Hochschulschrift KIT, KITopenID:1000169964 |
| Enhancing CNN‐LSTM neural networks using jellyfish search algorithm for pandemic modeling | Feriz, A.H. / Jalali, M. / Forghani, Y. (2024)
|
Concurrency Computat Pract Exper., 2024, e8123, doi 10.1002/cpe.8123 |
| 10th Anniversary of Inorganics: Inorganic Materials | Nisticò, R. / Idriss, H. / Carlos, L. / Aneggi, E / Jensen, T. (2024) |
Inorganics 2024, 12, 3, 62, doi.org/10.3390/inorganics12030062 |
| Optimized Detection of Volatile Organic Compounds Utilizing Durable and Selective Arrays of Tailored UiO-66-X SURMOF Sensors | Okur, S. / Hashem, T. / Bogdanova, E. / Hodapp, P. / Heinke, L. / Bräse, S. / Wöll, C. (2024) |
ACS Sens., 2024, 9, 2, 622–630, doi.org/10.1021/acssensors.3c01575 |
| A Core and Valence-Level Spectroscopy Study of the Enhanced Reduction of CeO2 by Iron Substitution—Implications for the Thermal Water-Splitting Reaction | Idriss, H. (2024) |
Inorganics 2024, 12, 2, 42, doi.org/10.3390/inorganics12020042 |
| Investigating Dynamic Changes in 3D-Printed Covalent Adaptable Polymer Networks | Jia, Y. / Tsotsalas, M. / Spiegel, C. / Zimmermann, D. / Blasco, E. / Wilhelm, M. / Huber, B. / Mutlu, H. / Theato, P. / Diehm, J. / Franzreb, M. (2024) |
Forschungsdaten KIT |
| Ultrastrong Electron‐Phonon Coupling in Uranium‐Organic Frameworks Leading to Inverse Luminescence Temperature Dependence | Chen, H. / Vankova, N. / Jha, G. / Yu, X. / Wang, Y. / Lin, L. / Kirschhöfer, K. / Greifenstein, R. / Redel, E. / Heine, T. / Wöll, C. (2024) |
Angew. Chem. Int. Ed. 2024, e202318559 |
| Exploration of metal-organic framework thin films assembled by polycyclic aromatic molecules for high-performance photodetectors | Xu, Z. / Wöll, C. / Bräse, S. (2024) |
Hochschulschrift KIT, KITopen-ID: 1000168300 |
| Water Oxidation over Au-Pd/TiO2 as a Substitute for Iridium-Based Catalysts | Idriss, H. / Wahab, K. (2024) |
Catalysts 2024, 14(1), 87, doi.org/10.3390/catal14010087 |
| Photoswitchable Radical State in Nanoporous Metal–Organic Framework Films with Embedded Hexaarylbiimidazole | Liu, Y. / Jiang, Y. / Heinke, L. (2024) |
Langmuir 2024, 40, 1, 474–479 |
| Lotus effect optimization algorithm (LEA): a lotus nature-inspired algorithm for engineering design optimization | Elham, D. / Mehrdad, J. / Mahdi, Y. / Hamid, T. (2024) |
The Journal of Supercomputing, 2024, 80,761–799 |
| Titel | chair | place |
|---|---|---|
| Cocktail of lipophilic and hydrophilic chemotherapeutics in high-load core@shell nanocarriers to treat pancreatic tumours | Rudolph, D. / Ischyropoulou, M. / Pfeifer, J. / Napp, J. / Schepers, U. / Alves, F. / Feldmann, C. (2024) |
Nanoscale Adv., 2024,6, 973-984 |
| Additive Fertigung von artifiziellen vaskulären Gewebemodellen mit Hilfe von 3D-Biodruckverfahren | Leopold, S. / Schepers, U. / Hartwig, A. (2024) |
Hochschulschrift KITopenID: 10000169316 |
| Entwicklung von Hydrogelen zur Herstellung von Organmodellen mit dem 3D-Biodruckverfahren | Grimm, A. / Schepers, U. / Köberle, B. (2024) |
Hochschulschrift KITopen ID: 10000169294 |
| Block Polyelectrolyte Additives That Modulate the Viscoelasticity and Enhance the Printability of Gelatin Inks at Physiological Temperatures | Göckler, T. / Albreiki, F. / Li, D. / Grimm, A. / Mecklenburg, F. / Urueña, J. / Schepers, U. (2024) |
ACS Appl. Polym. Mater., 2024, 6, 5, 2427–2441, doi.org/10.1021/acsapm.3c01085 |
| Peptoide als potentielle antibiotische Wirkstoffe gegen multiresistente Bakterien | Fleck, B. / Schepers, U. (2019/2024) |
Hochschulschrift KITopen-ID: 1000099094 |
| In vitro Rekonstruktion des Lebersinusoids im mikrofluidischen Organ-on-a-Chip System als humanes Modell zur verbesserten Wirkstoffentwicklung | Buntz, H. / Schepers, U. / Breitling, F. (2024) |
Hochschulschrift, KITopen-ID: 1000162341 |