Bio-orthogonal “Double-Click” Chemistry Based on Multifunctional Coatings

  • chair:

    Deng, X. / Friedmann, C. / Lahann, J. (2011)
  • place:

    Angewandte Chemie International Edition 29 (2011), 50
  • Date: 2011

  • Deng, X. / Friedmann, C. / Lahann, J. (2011): „Bio-orthogonal “Double-Click” Chemistry Based on Multifunctional Coatings“. In: Angewandte Chemie International Edition 29 (2011), 50

Abstract

Two different molecules can be sequentially immobilized on defined areas of the same surface by utilizing the different reactivity of activated and non-activated alkynyl groups. The reactions were carried out at room temperature in water, with the first immobilization step being catalyst-free and the second step requiring Cu as a catalyst.

 

 

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